Two factors in particular must be considered here. Relevant damage mechanisms can change from the HCF to the VHCF regime. For example, the crack initiation points shift into the volume in the field of defects, such as inclusions and precipitates, especially in the case of high-strength conditions. In the case of ductile materials, damage development can also be detected below the critical threshold value for the activation of persistent sliding bands, which can be attributed in particular to the high number of cycles and the associated accumulation processes. For this reason, it is necessary to check which of the measurement techniques used so far can also be used for the range of high numbers of cycles. The deformation rate or test frequency has a significant influence on the damage development per cycle. Higher test frequencies generally lead to an extension of the service life. It is essential that the relationship between frequency and damage contribution and the resulting fatigue life can be quantified and thus made usable for LPV. The aim is therefore to develop LPV for the use in the VHCF range and to implement influences with regard to deformation rate and stress-related mechanisms in mathematical approaches and to validate the prediction quality through experiments.