Veröffentlichungen ab 2010
Zeitschriftenartikel – “peer-reviewed”:
Scholz, P., Keck, C.M., Nanocrystals: From raw material to formulated final oral dosageform. A review. Current Pharmaceutical Design, accepted manuscript
Scholz, P., Keck, C.M. (2015), Nanoemulsions produced by rotor-stator high speed stirring. Int J Pharm. 482(1-2):110-7
Scholz, P., Keck, C.M. (2015), Flavonoid nanocrystals produced by ARTcrystalR-technology. Int J Pharm. 482(1-2):27-37
Romero G.B., Chen R., Keck C.M., Muller R.H. (2015) Industrial concentrates of dermal hesperidin smartCrystals R - production, characterization & long-term stability. Int. J. Pharm. 482(1-2
Wei Q., Keck C.M., Muller R.H. (2015), CapsMorphR technology for oral delivery - theory, preparation and characterization.Int J Pharm. 482(1-2):11-20
Lohan S.B., Bauersachs S., Ahlberg S., Baisaeng N., Keck C.M., Muller R.H., Witte E., Wolk K., Hackbarth S., Roder .B, Lademann J., Meinke M.C. (2015) Ultra-small lipid nanoparticles promot
Keck, C. M., Baisaeng, N., Durand, P., Prost, M., Muller, R. H. (2014) Oil-enriched, ultra-small Nanostructured Lipid Carriers (usNLC): a novel delivery system based on flip-flop structure.
Zhai X., Lademann J., Keck C.M., Muller R.H. (2014), Dermal nanocrystals from medium soluble actives - physical stability and stability affecting parameters. Eur. J. Pharm. Biopharm. 88(1):
Muller, I., Hartmann, D., Urbschat, S., Keck, C.M., Eichler, H. (2014), Static Image Analysis as New Approach for the Characterization of Tumor Cell Lysate Used in Dendritic Cell Vaccine Pr
Keck, C. M., Kovacevic, A., Muller, R. H., Savic, S., Vuleta, G., & Milic, J. (2014). Formulation of solid lipid nanoparticles (SLN): The value of different alkyl polyglucoside surfactants.
Zhai,X., Lademann, J., Keck, C.M., Muller, R. H. (2014) Nanocrystals of medium soluble actives – novel concept for improved dermal delivery and production strategy, Int. J. Pharm, 470(1-2):
Al Shaal, L., Mishra, P.R., Muller, R.H. and C.M. Keck (2014), Nanosuspensions of hesperetin: preparation and characterization, Die Pharmazie, 69(3), 173-82.
Muller, R. H., Staufenbiel, S., & Keck, C. M. (2014). Lipid Nanoparticles (SLN, NLC) for innovative consumer care & household products. H&PC Today, 9(2), 18-25.
Scholz, P., Arntjen, A., Muller, R.H., Keck, C.M. (2014) ARTcrystalR process for industrial nanocrystal production - Optimization of the ART MICCRA pre-milling step, Int. J. Pharm, 465(1-2)
Al Shaal, L., Mishra, P.R., Muller, R.H. and C.M. Keck (2014), Nanosuspensions of hesperetin: preparation and characterization, Die Pharmazie. 3: doi: 10.1691/ph.2014.3032
Keck, C.M., Anantaworasakul, P., Patel, M., Okonogi, S., Singh, K.K., Roessner, D., Scherrers, R., Schwabe, K., Rimpler, C., Muller, R.H. (2014) A new concept for the treatment of atopic de
Kovacevic, A.B., R.H. Muller, S.D. Savic, G.M. Vuleta and C.M. Keck (2014), Solid lipid nanoparticles (SLN) stabilized with polyhydroxy surfactants: Preparation, characterization and physic
Keck, C.M., Chen R., Muller R.H. (2013) smartCrystals for consumer care & cosmetics: enhanced dermal delivery of poorly soluble plant actives. H&PC Today, 8(5): p. 18-24.
Riangjanapatee P., Muller R.H., Keck C.M,. Okonogi S. (2013) Development of lycopene-loaded nanostructured lipid carriers: effect of rice oil and cholesterol. Die Pharmazie 68(9): p. 723-31
Acar Kubart, S., Keck, C.M. (2013) Laser diffractometry of nanoparticles. frequent pitfalls & overlooked opportunities. J Pharm Tech Drug Res, 2(1), dx.doi.org/10.7243/2050-120X-2-17
Schwarz, J.C., Baisaeng, N. Hoppel, M., Low, M., Keck, C.M., Valenta C., (2013) Ultra-small NLC for improved dermal delivery of coenyzme Q10. Int J Pharm, 447(1-2):213-7
Keck, C.M. Muller, R.H., (2013), Nanotoxicological Classification system (NCS) – a guide for risk-benefit assessment of nanoparticulate drug delivery systems. Eur J Pharm Biopharm, 84(3):44
Muchow, M., Maincent P., Muller R.H., Keck C.M., (2013) Testosterone undecanoate – increase of oral bioavailability by nanostructured lipid carriers (NLC). J Pharm Tech Drug Res, 2(1) dx.do
Rachmawati, H., Shaal L.A., Muller R.H., Keck C.M., (2013) Development of curcumin nanocrystal: Physical aspects. J Pharm Sci 102: 204-14
Keck, C.M., M. Jansch, R.H. Muller, (2013), Protein adsorption patterns & analysis on i.v. nanoemulsions – the key factor determining the organ distribution. Pharmaceutics, 5: 36-68
Keck, C.M., (2012) Partikelgrosenanalytik fur Nanopartikel: Ein Kinderspiel oder doch eine verflixte Kiste?, TechnoPharm, 4, 279-87
Kobierski, S., K. Ofori-Kwakye, R.H. Muller, C.M. Keck, (2011) Resveratrol nanosuspensions: Interaction of preservatives with nanocrystal production. Die Phamazie, 66 (12): 942-7
Haag, S.F., Chen M., Peters D., Keck C.M., Taskoparan B., Fahr A., Teutloff, C., Bittl, R., Lademann, J., Schafer- Korting, M., Meinke, M.C., (2011) Nanostructured lipid carriers as nitroxi nanoemulsions for intravenous drug delivery. Drug Dev Ind Pharm, 38(4):420-30
Muller, R.H., D. Harden, C.M. Keck, Development of industrially feasible concentrated 30% & 40% interaction between lipid nanoparticles and organic UV filters. Int J Pharm; 414: 276-84
Nikolic, S., Keck C.M., Anselmi C., Muller R.H., (2011) Skin photoprotection improvement: synergistic
Muller, R.H., C.M. Keck, (2011) Twenty years of drug nanocrystals: Where are we, and where do we go? Eur J Pharm Biopharm, 80: 1-3
Muller, R.H., R. Shegokar, C.M. Keck, (2011) 20 Years of Lipid Nanoparticles (SLN and NLC): Present State of Development and Industrial Applications. Curr Drug Discov Technol, 8 (3): 207-27
Muller, R.H., S. Gohla, C.M. Keck, (2011) State of the art of nanocrystals - Special features, production, nanotoxicology aspects and intracellular delivery. Eur J Pharm Biopharm, 2011. 78:
Kovacevic, A., S. Savic, G. Vuleta, R.H. Muller, C.M. Keck, (2011) Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): Effects on size, physical stability and
Souto, E. B., Keck, C.M., Muller, R.H. (2011). Technology of Lipid Nanoparticles (SLN, NLC) as nanocarriers for skin applications: Properties, Production & Cosmetic Formulations, Skin Res.
Muchow, M., Maincent, P., Muller, R.H., Keck, C.M. (2011). Production and Characterisation of testosterone undecanoate-loaded NLC for oral bioavailability enhancement, Drug Dev. Ind. Pharm.
Obeidat, W.M., Schwabe, K., Muller, R. M., Keck, C.M. (2010). Preservation of Nanostructured Lipid Carriers (NLC), Eur. J. Pharm. Biopharm., 76(1): 65-67
Al Shaal L., Muller R.H., Keck C.M., (2010). Preserving Hesperetin nanosuspensions for dermal application, Die Pharmazie, 65 (2): 86-92
Keck, C.M. (2010). Particle size analysis of nanocrystals: Improved analysis method, Int. J. Pharm., 390 (1):3-12 C. Keck – Anlage 13
Muller, R.H., Keck, C.M., (2010). Pharmaceutical nanoparticles - from their innovative origin to their future, Int. J. Pharm., 390 (1): 1-2
Baspinar, Y., Keck, C.M., Borchert, H.-H. (2010). Positively charged prednicarbate nanoemulsions for the treatment of atopic dermatitis, Int. J. Pharm., 383 (1-2): 201-08
Staedtke, V., Brahler, M., Muller, A., Georgieva, R., Bauer, S., Sternberg, N., Voigt, A., Lemke, A., Keck, C.M., Moschwitzer, J., Baumler, H. (2010). In vitro inhibition of fungal activity
Zeitschriftenartikel – „non peer-reviewed“:
Keck, C.M., Muller, R.H. (2014). нанокосметика Женщина-мечта античности, Lab & More Russia, 1:14, p.1-7.
Muller, R.M., P. Sinambela and C.M. Keck (2013). NLC – the invisible dermal patch for moisturizing & skin protection. EURO COSMETICS,6: p. 20-22.
Keck, C.M., Muller, R.H. (2013). Auf den Spuren Kleopatras Schonheit und warum Nanotechnologie noch schoner macht, Labor & More, 1.13: 8-15.
Keck, C.M. , Klotz, M., Schafer, K.-H., Muller, R.H. (2011). Proteinanalytik – Schlussel zum Korper, Labor & More, 1: 52-54.
Keck, C.M. , Muller, R.H. (2010). Silber-Lipid-Zwerge - Ein neues Therapiekonzept gegen Neurodermitis, Quantos, 1: 6-11.
Proceedings (mehrseitig):
Keck, C. M., Pyo, S. M., Jin, N., Muller, R. H., Knauer, J., Rutin smartCrystals - most effective anti-oxidant activity & skin penetration, p. 14, Menopause, Andropause, Anti-aging, Vienna, 11.-13. Dezember 2014
Jin, N., Staufenbiel, S., Keck, C. M., Muller, R. H., smartCrystals - enhancement of drug penetration without penetration enhancer, p. 13, Menopause, Andropause, Anti-aging, Vienna, 11.-13. Dezember 2014
Keck, C. M., Monsuur, F., Hofer, H. H., Jin, N., Staufenbiel, S., Muller, R. H., smartPearls - new dermal injection-like delivery system without use of a needle, p. 10, Menopause, Andropause, Anti-aging, Vienna, 11.-13. Dezember 2014
Wei, Q., Staufenbiel, S., Muller, R. H., Keck, C. M., CapsMorph: controlled release of poorly water-soluble drug by using porous silica material, W5172, AAPS Annual Meeting, San Diego, 2-6 November 2014
Scholz, P., Staufenbiel, S., Muller, R. H., Keck, C. M., Method for the production of drug nanocrystals in industrial scale, W4347, AAPS Annual Meeting, San Diego, 2-6 November 2014
Muller, R. H., Ruick, R., Keck, C. M., smartLipidsR - the new generation of lipid nanoparticles after SLN and NLC, T3134, AAPS Annual Meeting, San Diego, 2-6 November 2014
Romero, G. B., Keck, C. M., Muller, R. H., Preservation of smartCrystalR suspensions for functional drinks, T2131, AAPS Annual Meeting, San Diego, 2-6 November 2014
Romero, G. B., Keck, C. M., Muller, R. H., Simple downscaling approach for nanocrystal production, R6262, AAPS Annual Meeting, San Diego, 2-6 November 2014
Staufenbiel, S., Jin, N., Keck, C. M., Muller, R. H., Determination of surface hydrophobicity and protein adsorption onto differently coated azithromycin nanocrystals, R6080, AAPS Annual Meeting, San Diego, 2-6 November 2014
Li, X., Zhai, X., Romero, G. B., Keck, C. M., Muller, R. H., Physical stability of nanocrystals in hydrogels and o/w creams, M1184, AAPS Annual Meeting, San Diego, 2-6 November 2014
Staufenbiel, S., Reinicke, A., Supplies, M., Keck, C. M., Muller, R. H., NanoCoffee - a dermal formulation with high antioxidant capacity and peeling effect, M1103, AAPS Annual Meeting, San Diego, 2-6 November 2014
Jin, N., Staufenbiel, S. Keck, C. M., Muller, R. H., Development of dermal azithromycin nanocrystals for prevention of lyme borreliosis, M1102, AAPS Annual Meeting, San Diego, 2-6 November 2014
Li, X., Zhai, X., Romero, G. B., Keck, C. M., Muller, R. H., Physical stability of nanostructured lipid carriers (NLC) in hydrogels, M1095, AAPS Annual Meeting, San Diego, 2-6 November 2014
Muller, R. H., Pyo, S., Zhai, X., Klein, S., Fischer, T., Keck, C. M., Combined nanocrystal-NLC formulation for laser co-treatment of couperosis, M1079, AAPS Annual Meeting, San Diego, 2-6 November 2014
Muller, R. H., Schmidt, C., Trebeljahr, R., Lautenschlager, H., Keck, C. M., Boswellia smartCrystals for dermal application: production and stability, M1078, AAPS Annual Meeting, San Diego, 2-6 November 2014
Romero, G. B., Keck, C. M., Muller, R. H., Chacra, N., Cationic dexamethasone acetate-polymyxin B nanocrystals: an innovative strategy for the treatment of ophthalmic infections, FCF 91, XIX Pharmaceutical Science and Technological Meeting, Sao Paulo, 20-24 October 2014 C. Keck – Anlage 119
Li, X., Keck, C. M., Muller, R. H., Zhai, X., Chacra, N., Cationic nanoemulsions as potential ophthalmic delivery system for dexamethasone acetate and polymyxin B, FCF 115, XIX Pharmaceutical Science and Technological Meeting, Sao Paulo,20-24 October 2014
Muller, R.H., Monsuur, F., Hofer H.H., Jin, N., Staufenbiel, S., Keck, C.M. (2014) smartPearlsTM - novel amorphous delivery system based on porous materials to increase skin penetration of anti-oxidants, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, p19
Junmahasathien, T., Muller, R.H., Keck, C.M. (2014) Myristyl nicotinate-loaded Nanostructured Lipid Carriers for improved dermal delivery, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing,1– 3 October, Metz, France, p15
Jin, N., Staufenbiel, S., Arntjen, A., Keck, C.M., Muller, R.H. (2014) Azithromycin nanocrystals for topical prevention of systemic Lyme Borreliosis infection, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, p14
Gerst, M., Rostamizadeh, K., Arntjen, A., Scholz, P., Keck, C.M. (2014) Art Crystal Technology for Improved Dermal Penetration of Rutin Nanocrystals, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, p13
Rostamizadeh, K., Keck, C.M. (2014) Physicochemical characterization of Nanostructured Lipid Carriers (NLC): impact of solid Lipid to liquid lipid ratio, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, Nutri-Ox 2014: Nutrition and Ageing, 1 – 3 October, Metz, France, p12
Scholz, P., Gerst, M., Keck, C.M. (2014) ARTcrystalR-technology to improve the bioactivity of poorly soluble plant actives, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing,1 – 3 October, Metz, France, p10
Lohan,S.B., Bauersachs, S., Ahlberg, S., Baisaeng,N., Keck,C.M., Muller, R. H.,Witte, E., Wolk,K., Hackbarth, S., Roder,B., Lademann,J., Meinke, M.C. (2014) Improved protection against oxidative stress by Ultra-small lipid nanoparticlesusNLC) loaded with Coenzyme Q10, Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, p5
Muller , R.H., Chen, R., Durand, P.,Prost, M., Keck, C.M. (2014) Nanocrystals for Improved Antioxidant Capacity of Flavonoids, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, p1
Baisaeng, N. Rostamizadeh, K. Muller, R.H. Lohan, S. Meinke, M. C. Durand, P. Prost, M., Keck, C.M. (2014) Flip Flop NLC for improved delivery of natural antioxidants, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz, France, communication 7
Arntjen, A., Maus, A., Keck, C.M. (2014) Skin hydration of NLC due to formation of invisible patch: influence of vehicle, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.28
Muller, R.H., Ruick, R., Keck, C.M. (2014) smartLipids – the next generation of lipid nanoparticles by optimized design of particle matrix, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a.M., Germany, PT.27
Rostamizadeh, K., Gerst, M., Scholz, P., Arntjen, A., Keck, C.M. (2014) “Nano-Curry” for improved health, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.19
Hommoss, G., Keck, C.M., Zhai, X., Muller, R.H. (2014) Tetrahydrocannabinol-loaded NLC for nasal drug delivery against break-through pain in cancer patients, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.17
Romero, G.B., Keck. C.M., Muller, R.H., Bou-Chacra, N.A. (2014) Mucoadhesive polymyxin B-dexemtasone acetate nanocrystals for ocular delivery, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a.M., Germany, PT.16
Pyo, S.M., Meinke, M.C., Keck, C.M., Muller, R.H. (2014) Dermal delivery systems – nanoemulsion vs. nanostructured lipid carriers (NLC), Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.12 C. Keck – Anlage 118
Scholz, P., Muller, R.H., Keck, C.M. (2014) ARTcrystal-tehnology for nanocrystal production: comparison of continuous premilling step, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.11
Jin, N., Staufenbiel, S., Keck, C.M., Muller, R.H. (2014) Pig ear skin penetration of azithromycin nanocrystals for Lyme Borreliosis infection, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.09
Romero, G.B., Keck, C.M., Muller, R.H. (2014) Small scale production of nanocrystals in drug discovery and development phase, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.8
Jin, N., Staufenbiel, S., Arntjen, A., Schafer, K.-H.,Keck, C.M., Muller , R.H. (2014) Evaluation of dermal azithromycin nanocrystals for lyme borreliosis infection, 3rd International Conference in Advanced Manufacturing for Multifunctional Miniaturised Devices, Tsukuba, Japan, 27– 28 August, 2014
Arntjen, A., Gerst, M.; Maus, A., Keck, C.M. (2014) Nanocarrier zur dermalen Applikation, Wirk- und Effektstoff-Forschung RLP: Screening, Synthese, Wirkung & Verfahrenstechnik“, Kaiserslautern 23. Juni 2014
Scholz, P., Keck, C.M. (2014) Prozessentwicklung und -optimierung in der Herstellung nanopartikularer Arzneistoffsysteme, Wirk- und Effektstoffforschung RLP: Screening, Synthese, Wirkung & Verfahrenstechnik, Kaiserslautern, 23 June 2014
Scholz, P., Muller, R.H., Keck, C.M. (2014) ARTcrystalR-technology: Influence of starting material size on final particle size „Tag der Pharmazie“, DPhG Landesgruppe Berlin-Brandenburg, Berlin, 4. Juli 2014
Keck, C.M. (2014) Improved efficacy of antioxidants through innovative dermocosmetic formulations, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Keck, C.M. (2014) Silver-nano-lipid complex (sNLC) as a new therapy concept for atopic dermatitis, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Staufenbiel, S., Jin, N., Keck, C. M., Muller, R. H. (2014) Surfactant optimization for dermal azithromycin nanocrystals, P18, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Sinambela, P., Muller, R. H., Keck, C. M., Knauer, J. (2014) Dermal formulations with rutin nanocrystals & peptide-loaded liposomes - mechanisms & in vivo performance, P17, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 07-09. Apr 14
Lohan, S., Bauersachs,S. ,Ahlberg, S., Baisaeng, N., Keck, C.M., Lademann, J., Meinke M.C. (2014) Ultra-small nanoparticles promote the penetration of CoQ10 in the skin - a counteract against oxidative stress, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Romero, G. B., Keck, C. M., Muller, R. H. (2014) Ultra fine cyclosporine A nanocrystals produced in a super small scale, P15, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Pyo, S. M., Meinke, M. C., Muller, R. H., Keck, C. M. (2014) Nanocrystals - a "needle free injection" of drug into the skin, P14, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Jin, N., Staufenbiel, S., Keck, C. M., Muller, R. H. (2014) Improved solubility properties of topical azitrhomycin nanocrystals for prophylaxis of borreliosis infection, P7, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Hu, X., Keck, C. M., Muller, R. H. (2014) Laser diffractometry size analysis of nanoparticles: the ignored pitfall of refractive indices!, P6, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Zhai, X., Staufenbiel, S.,Keck, C. M., Muller, R. H. (2014) Ultrafine gelatin nanoparticles for dermal delivery of peptides & enzymes: production and characterization, P. 41, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13-14 March, 2014
Scholz, P., Keck, C.M. (2014) Comparison of the nanonization potential of high speed stirring and pearl milling, 9th European Workshop on Particulate Systems in Nanomedicine, 13-14 March 2014
Pyo, S. M., Romero, G. B., Keck, C. M., Muller, R. H. (2014) Nano lipid carriers (NLC) & nanocrystal formulation for couperosis treatment, P. 39, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13-14 March, 2014
Pyo, S.M., Meinke, M.C., Keck, C.M., Muller, R.H. (2014) Dermal delivery systems – nanoemulsion vs. nanostructured lipid Jin, N., Staufenbiel, S. Helf, T., Muller, R. H. (2014) Comparison of methods to produce dermal azithromycin nanosuspensions to prevent lyme borreliosis infection, P. 38, 11th European Workshop on ParticulateSystems(EWPS), Utrecht, 13-14 March, 2014
Scholz, P., Muller, R.H., Keck, C.M. (2014) ARTcrystal-tehnology for nanocrystal production: comparison of continuous premilling step, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.11
Jin, N., Staufenbiel, S., Keck, C.M., Muller, R.H. (2014) Pig ear skin penetration of azithromycin nanocrystals for Lyme Borreliosis infection, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.09
Romero, G.B., Keck, C.M., Muller, R.H. (2014) Small scale production of nanocrystals in drug discovery and development phase, Annual Meeting of the German Pharmaceutical Society (DPHG), 24-26 September, Frankfurt a. M., Germany, PT.8
Jin, N., Staufenbiel, S., Arntjen, A., Schafer, K.-H.,Keck, C.M., Muller , R.H. (2014) Evaluation of dermal azithromycin nanocrystals for lyme borreliosis infection, 3rd International Conference in Advanced Manufacturing for Multifunctional Miniaturised Devices, Tsukuba, Japan, 27– 28 August, 2014
Arntjen, A., Gerst, M.; Maus, A., Keck, C.M. (2014) Nanocarrier zur dermalen Applikation, Wirk- und Effektstoff-Forschung RLP: Screening, Synthese, Wirkung & Verfahrenstechnik“, Kaiserslautern 23. Juni 2014
Scholz, P., Keck, C.M. (2014) Prozessentwicklung und -optimierung in der Herstellung nanopartikularer Arzneistoffsysteme, Wirk- und Effektstoffforschung RLP: Screening, Synthese, Wirkung & Verfahrenstechnik, Kaiserslautern, 23 June 2014
Scholz, P., Muller, R.H., Keck, C.M. (2014) ARTcrystalR-technology: Influence of starting material size on final particle size „Tag der Pharmazie“, DPhG Landesgruppe Berlin-Brandenburg, Berlin, 4. Juli 2014
Keck, C.M. (2014) Improved efficacy of antioxidants through innovative dermocosmetic formulations, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Keck, C.M. (2014) Silver-nano-lipid complex (sNLC) as a new therapy concept for atopic dermatitis, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Staufenbiel, S., Jin, N., Keck, C. M., Muller, R. H. (2014) Surfactant optimization for dermal azithromycin nanocrystals, P18, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Sinambela, P., Muller, R. H., Keck, C. M., Knauer, J. (2014) Dermal formulations with rutin nanocrystals & peptide-loaded liposomes - mechanisms & in vivo performance, P17, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin ,07-09. Apr 14
Lohan, S., Bauersachs,S. ,Ahlberg, S., Baisaeng, N., Keck, C.M., Lademann, J., Meinke M.C. (2014) Ultra-small nanoparticles promote the penetration of CoQ10 in the skin - a counteract against oxidative stress, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Romero, G. B., Keck, C. M., Muller, R. H. (2014) Ultra fine cyclosporine A nanocrystals produced in a super small scale, P15, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Pyo, S. M., Meinke, M. C., Muller, R. H., Keck, C. M. (2014) Nanocrystals - a "needle free injection" of drug into the skin, P14, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Jin, N., Staufenbiel, S., Keck, C. M., Muller, R. H. (2014) Improved solubility properties of topical azitrhomycin nanocrystals for prophylaxis of borreliosis infection, P7, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Hu, X., Keck, C. M., Muller, R. H. (2014) Laser diffractometry size analysis of nanoparticles: the ignored pitfall of refractive indices!, P6, Jahrestagung der Gesellschaft fur Dermopharmazie (GD), Berlin, 7-9 April, 2014
Zhai, X., Staufenbiel, S.,Keck, C. M., Muller, R. H. (2014) Ultrafine gelatin nanoparticles for dermal delivery of peptides & enzymes: production and characterization, P. 41, 11th European Workshop on Particulate Systems (EWPS), U tr echt , 13-14 March, 2014
Scholz, P., Keck, C.M. (2014) Comparison of the nanonization potential of high speed stirring and pearl milling, 9th European Workshop on Particulate Systems in Nanomedicine, 13-14 March 2014
Pyo, S. M., Romero, G. B., Keck, C. M., Muller, R. H. (2014) Nano lipid carriers (NLC) & nanocrystal formulation for couperosis treatment, P. 39, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13-14 March, 2014
Jin, N., Staufenbiel, S. Helf, T., Muller, R. H. (2014) Comparison of methods to produce dermal azithromycin nanosuspensions to prevent lyme borreliosis infection, P. 38, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13 -14 March, 2014
Wei, Q., Chen, R., Muller, R. H., Keck, C. M., Amorphous CapsMorph with high drug loading capacity for oral formulation, p. 31, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13-14 March, 2014 C. Keck – Anlage 117
Romero, G. B., Keck, C. M., Muller, R. H. (2014) Long-term stability of smartCrystals from poorly soluble plant actives, p. 25, 11th European Workshop on Particulate Systems (EWPS), Utrecht, 13-14 March, 2014
Sinambela, P., Staufenbiel, S., Loffler, B. M., Egorov, E., Keck, C. M., Muller, R. H. (2013) Wrinkle reduction effect of rutin nanocrystals and peptide-loaded liposomes: a human in vivo study, R6087, AAPS Annual Meeting, San Antonio, 10-14. Nov 13
Romero, G. B., Keck, C. M., Muller, R. H. (2013)Production of small ascorbyl palmitate nanocrystals for dermal bioavailability enhancement, W4117, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Wei, Q., Muller, R. H., Romero, G. B., Keck, C. M. (2013) Solidification of nanocrystals formulation by spray drying, W5071, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Chen, R., Romero, G. B., Keck, C. M., Muller, R. H. (2013) Reproducibility of smartCrystal technology for large scale production of cosmetic hesperidin nanocrystals, W5006, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Hu, X., Keck, C. M., Muller, R. H. (2013) Stability study of dermal nano Q10 concentrates preserved by glycols, W5054, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Muller, R. H., Wei, Q., Keck, C. M. (2013) Stability of industrially feasible amorphous drug formulations generated in porous silica, W5313, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Chen, R., Prost, M., Durand, P., Greiner, L., Muller, R. H., Keck, C. M. (2013) Increased kinetic solubility and antioxidant capacity of tailor-made, quercetin nanocrystals, W5005, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Muller, R. H., Hohne, L., Keck, C. M. (2013) Betulin nanosuspensions for dermal delivery – production and caracterization, W5056, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Junmahasathien, T., Muller, R. H., Keck, C. M. (2013) Development of myristyl nicotinate-loaded nanostructured lipid carriers, W5055, AAPS Annual Meeting, San Antonio, 10-14 November 2013
Pyo, S. M., Keck, C. M., Muller, R. H. (2013) Vitamin K1-loaded NLC – optimization of production and formulation, NM.22, DPhG-Jahrestagung, Freiburg, 9.-11. Oktober 2013
Hohne, L., Keck, C. M., Muller, R. H. (2013) Optimized production and characterization of betulin nanocrystals for dermal application, NM.04, DPhG-Jahrestagung, Freiburg, 9.-11. Oktober 2013
Romero, G. B., Keck, C. M., Muller, R. H., Improved physical stability of layer-by-layer (LbL) coated nanocrystals (2013), NM.02, DPhG-Jahrestagung, Freiburg, 9.-11. Oktober 2013
Staufenbiel, S., Groger, D., Keck, C. M., Haag, R., Muller, R. H. (2013) Targeting of i. v. polymeric nanoparticles by differential protein adsorption, PLS-46, Berlin, 29 September – 2 October 2013
Staufenbiel, S. Keck, C. M., Muller, R. H. (2013) Concept for „real environment“ quantification of surface hydrophobicity of polymeric nanoparticles, 12th International Conference „Polymers for Advanced Technologies“, PLS-45, Berl in, 29 September – 2 October 2013
Eichler , H., Hartmann , D., Ecker , C., Keck , C. M. (2013) A new approach for analysing avitality of tumor cell lysate used in dendritic cell vaccination trials, 46th Jahreskongress Deutsche Gesellschaft fur Transfusionsmedizin und Imunhamatologie (DGTI), ZTH-P0,Munster, 24-27 September 2013
Muller, I., Hartmann, D., Ecker, C., Keck, C.M., Eichler, H. (2013) Static Image analysis to determine the aviality of tumor cell lysate in dendritic cell vaccination trials, 46th Jahreskongress Deutsche Gesellschaft fur Transfusi on smed iz in und Immunhamatologie (DGTI), ZTH-P0,Munster, 24-27 September 2013
Boreham, A., Schlieter, T., Volz, P., Balke, J., Peters, D., Keck, C., Alexiev, U. (2013)"Two different approaches to tracking individual fluorophores: application to lipid nanocarriers and their internal structure 9th European Biophysics Congress EBSA 13-17 July Lisbon/Portugal.
Keck, C.M., Baisaeng, N., Peters, D., Muller R.H (2013) The potential antioxidant capacity of coenzyme Q10-loaded ultrasmall lipid nanocarriers (usNLC), 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Muller R.H., Wie Q., Keck, C.M. (2013) CapsMorph: >4 Years Long-Term Stability of Industrially Feasible Amorphous Drug Formulations, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Keck, C.M., Muller R.H., Junmahasathien, T. (2013) The influence of energy input on producing Nanostructured Lipid Carriers, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May. C. Keck– Anlage 1 16
Keck, C.M., Kovacevic, A., Savic, S., Milic, J., Muller, R.H. (2013) Sucrose esters in the lipid nanoparticles formulation, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Keck, C.M., Kovacevic, A., Savic, S., Milic, J., Muller, R.H. (2013) Development of nanostructured lipid carriers (NLC) formulations stabilized with sugar ester, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Keck, C.M., Muller R.H. (2013) New developments in dermal delivery with lipid nanoparticles & drug nanocrystals, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Chen, R., Prost M., Greiner L., Muller R. H., Keck C. M. (2013) Size-dependent Antioxidant Capacity of Tailormade Quercetin Nanocrystals: a quick look from KRL Test, 7th German-Polish Symposium "New Challenges for Pharmaceutical Sciences", Gdansk/Poland, 24-25 May.
Zhai, X., Keck, C.M., Muller, R.H. (2013) Caffeine Nanocrystals – novel concept for improved dermal delivery & production method, Annual Meeting of the Society of Dermopharmacy, Mainz/Germany, 21-23 March.
Keck, C.M. (2013) Lamellare Formulierungen als Rezepturgrundlagen – von der High-Tech-Analyse bis zur Identitatskontrolle in der Apotheke, Annual Meeting of the Society of Dermopharmacy, Mainz/Germany, 21-23 March.
Keck, C.M. (2013) Galenische Besonderheiten von Dermokosmetika zur Anwendung bei zu Akne neigender Haut, Annual Meeting of the Society of Dermopharmacy, Mainz/Germany, 21-23 March.
Junmahasathien, T., Muller, R.H., Keck, C. M. (2013) Ultra-small scale for hot extrusion nanoparticle production, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 21-32 March.
Bohrer, B., Keck, C.M., Gansen, P., Muller, R.H., Dittgen, M. (2013) Polyurethan transdermal patches loaded with Ibuprofen, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 21-32 March.
Xiangyu, L., Chen, R., Baisaeng, N., Muller, R. H., Keck, C. M. (2013) Surfactants for the formulation of NLC: Effects on size and physical stability, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 21-32 March.
Junmahasathien, T., Baisaeng, N., Schwarz, J.C., Muller, R. H., Valenta, C., Keck, C.M. (2013) CoQ10-loaded ultrasmall lipid nanocarriers (usNLC) for the deeper penetration, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 2 Jan 32March.
Chen, R., Xiangyu, L., Muller, R.H., Keck, C.M. (2013) Improvement of Kinetic Solubility of Tailor-made Quercetin Nanocrystals, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 21-32 March.
Chen, R., Sauer, M., Durand, P., Muller, R.H., Schafer, K.-H., Prost, M., Keck, C.M. (2013) Rutin Nanocrystals: Production, Antioxidative Capacity, Neuroprotection, CRS German Chapter Annual Meeting, Ludwigshafen/Germany, 21-32 March.
Sinambela, P., Egorov, E., Loffler, B.M., Knauer, J., Muller, R.H., Keck, C.M. (2012) Antiaging rutin smartcrystals for reduction of brown and red skin spots – an in vivo study, Menopause-Andropause-Anti-Aging 2012, Vienna/Austria, 06. Aug December.
Sinambela, P., Egorov, E., Loffler, B.M., Muller, R.H., Keck, C.M. (2012) Combination of rutin smartCrystals and peptide-loaded liposomes for wrinkle reduction – an in vivo study, Menopause-Andropause-Anti-Aging 2012, Vienna/Austria, 6-8 December.
Junmahasathien, T., Muller, R.H., Keck, C.M. (2012). Development and stability of Novel nanostructured lipid carriers with coconut oil, The 4th International Conference on Natural Products for Health and Beauty (NATPRO 4), Chiang Mai/Thailand, 28 - 30 November.
Junmahasathien, T., Muller, R.H., Keck, C.M. (2012). Development of new Nanostructured Lipid Carriers (NLC): The optimum concentration and production condition, Deutsche Pharmazeutische Gesellschaft e.V. (DPhG), Greifswald/German 11-13 October.
Keck, C.M., Kovacevic, A., Muller, RH. (2012). Natural surfactant of polyglycerol fatty acid esters type as stabilizers for lipid nanoparticles, Annual Conference of the German Pharmaceutical Society, Greifswald/Germany, 11 – 13 October, submitted.
Junmahasathien, T., Muller, R.H., Keck, C.M. (2012). Comparison and stability of ultra-small scale and normal lab scale for producing lipid nanoparticles, Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), Chicago/USA, 14-18 October.
Acar Kubart, S., Muller, R.H., Keck. C.M. (2012). Stable ketoprofen microcrystals by LBLplus technology. in Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), Chicago/USA, 12 - 14 October.
Acar Kubart, S., Muller, R.H., Keck C.M. (2012). Amorphous itraconazole formulations by CapsMorph technology. in Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), Chicago/USA, 12 - 14 October. C. Keck – Anlage 115
Kovacevic, A., Muller, R.H., Savic, S., Keck, C.M. (2012). Develoment of a controlled release formulation for tacrolimus based on nanostructured lipid carriers (NLC), AAPS Annual Meeting and Exposition, Chicago/USA, 14 - 18 October.
Chen, R., Kumanova, O., Keck, C.M., Muller, R.H. (2012). ART nanocrystals: a novel combinational technology to produce drug nanocrystals - more efficient and economical, American Association of Pharmaceutical Scientists (AAPS) Annual Meeting & Exposition, Chicago/USA, 14 - 18 October.
Peters, D., Harden, D., Schmidt, C., Chen, R., Muller, R.H., Keck, C.M. (2012). Antioxidant capacity of omega 3 fatty acids - improvement by nanoemulsification, 26th Annual Meeting of American Association of Pharmaceutical Scientists (AAPS), Chicago/USA, 14 - 18 October.
Baisaeng, N., Muller, R.H., Keck, C.M. (2012). The physicochemical characterization of CoQ10-loaded ultrasmall lipid nanocarriers, AAPS Annual Meeting, Washington D.C./USA, 14 - 18 October
Chen, R., Wszelaki, N., Melzig, M. F., Muller, R.H., Keck, C.M. (2012). Tailor-made production of quercetin and rutin nanocrystals for investigating the correlation between the size and effect to cell, DPhG Jahrestatung, Greifswald, 11-13 October.
Annual Meeting of the German Biophysical Society (DGfB), 23–26 September, Gottingen7Germany
Boreham, A., Schlieter, T., Peters, D., Keck, C., Muller R., Alexiev, U. (2012) "Tracking individual flurophores: application to lipid nanocarriers and their internal structure"
Kovacevic, A., Muller, R.H., Keck, C.M., (2012). Physicochemical characterization of alkyl polyglucoside surfactants based lipid nanoparticles, 9th Central European Symposium on Pharmaceutical Technology, Dubrovnik/Croatia, 20 - 22 September.
Kovacevic, A., Muller, R.H., Scmhidt, C., Volz, I., Savic, S., Vuleta, G., Keck, C.M. (2012). Tacrolimus loaded nanostructured lipid carriers (NLC) formulation for dermal application, 9th Central European Symposium on Pharmaceutical Technology, Dubrovnik/Croatia, 20 - 22 September 2012.
Kovacevic, A., Muller, R.H., Savic, S., Vuleta, G., Keck, C.M. (2012). Influence of nonionic polyhydroxy surfactants on the formation of the lipid nanoparticles, 9th Central European Symposium on Pharmaceutical Technology, Dubrovnik/Croatia, 20 - 22 September.
Keck, C.M. (2012) Nanocarriers for Healthcare and Cosmetics: Nanocrystals and Nanolipids for improved delivery of actives, Nutrichemicals and their regulatory influences on intracellular processes (NutriOx 2012), Saarbrucken/Germany, 6-9 September.
Keck, C.M., Muller R.H. (2012) Influence of the surface properties of nanoparticles for drug targeting and toxicity Engineering of Functional Interfaces (EnFI), Zweibrucken/Germany, 16 - 17 July.
Acar Kubart, S., C.M. Keck, Muller R.H. (2012). CapsMorphTM – long term preservation of the amorphous state for poorly soluble actives. Engineering of Functional Interfaces (EnFI), Zweibrucken, 16 - 17 July.
Junmahasathien, T., Muller, R.H., Keck, C.M. (2012). Production of Nanoemulsion (NE) and Lipidnanoparticles in ultra-small scale, Engineering of Functional Interfaces (EnFI), Zweibrucken/Germany, 16-17 July.
Baisaeng, N., Muller, R.H., Keck, C.M. (2012). Development and production of ultra-small lipid nanocarriers (NLC), Engineering of Functional Interfaces (EnFI), Zweibrucken, 16 - 17 July.
Harden, D., Muller, R.H., Keck, C.M. (2012). Drug loaded omega-3-fatty-acid nanoemulsions for i. v. injection, „Tag der Pharmazie“, DPhG Landesgruppe Berlin-Brandenburg, Berlin, 6 July, P13.
Junmahasathien, T., Muller, R.H., Keck, C.M. (2012). Novel nanostructured lipid carriers using coconut oil. Tag der Pharmazie, Berlin/Germany, 6 July.
Chen, R., Wszelaki, N., Melzig, M. F., Muller, R.H., Keck, C.M. (2012). Production, characterization and neuroeffect of quercetin nanocrystals: Correlation between the size and cell penetrating. Tag der Pharmazie, Free University of Berlin, Berlin, 6 July, P6.
Peters, D., Muller, R.H., Keck, C.M. (2012). Improvement of the 50 year old standard AOC test, „Tag der Pharmazie“, DPhG Landesgruppe Berlin-Brandenburg, Berlin/Germany, 6 July, P24.
Sinambela, P., Loffler,B.M., Egorov, E., Shegokar, R.; Keck, C.M., Muller, R.H. (2012). Dermal application of rutin nanocrystals on human skin as cosmetic and anti-inflammatory formulation, Tag der Pharmazie, Annual Meeting, Berlin, 6 July, P 30,
Baisaeng, N., Muller, R.M., Keck, C.M. (2012). The development and production of ultra-small lipid nanocarriers, Tag der Pharmazie, Annual Meeting, Berlin, 6 July, P 03,C. Keck – Anlage 114
Acar Kubart, S., C.M. Keck. (2012). Einfluss von Primarpackmitteln auf Nano-Arzneistofftrager- Teil 1: Wasser. in 8. Veranstaltung der DPhG Landesgruppe Berlin-Brandenburg “Der wissenschaftliche Nachwuchs stellt sich vor”, Berlin, 6. July.
Acar Kubart, S., R.H. Muller, C.M. Keck. (2012). The secret of Cleopatra´s Beauty – and how Nanotechnology makes you even more beautiful in Spring Conference “Nanomedicine: Visions, risks, potential”, Berlin,19-20 April.
Harden, D., Muller, R.H., Keck, C.M., (2012). Zeta potentential analysis for optimized formulation development, CRS German Chapter Annual Meeting, Wurzburg/Germany, 29 - 30 March, P2-10,
Chen, R., Muller, R.H., Keck, C.M. (2012). LBLPlus - nanocrystals with enhanced stability in body fluids, CRS German Chapter Annual Meeting, Wurzburg/Germany, 29 - 30 March, P38, poster P2-11.
Peters, D., Harden, D., Schmidt, C., Muller, R.H., Keck, C.M. (2012). Comparison of antioxidant capacity of krill oil capsules vs. Alaska Pollock oil capsules, Controlled Release Society (CRS) German Chapter Annual Meeting, Wurzburg/Germany, 29 - 30 March, P5-4.
Baisaeng, N., Okonogi, Muller, R.H., Keck, C.M. (2012). In vitro release profile of coenzyme Q10-loaded ultrasmall lipid nanocarriers and nanostructuered lipid carriers (NLC), CRS German Chapter Annual Meeting, Wurzburg, 29-30 March, P13.
Kovacevic, A., Muller, R.H., Keck, CM. (2012). In vitro release of tacrolimus from the nanostructured lipid carriers (NLC), CRS German Chapter Annual Meeting, Wurzburg/Germany, 29-30 March, P 5-3.
Keck, C.M., Gohla S., Muller R.H. Anti-oxidative and skin protective effects of drug nanocrystals. In Gesellschaft fur Dermopharmazie. Annual Meeting of the Society of Dermopharmacy, 1-3 March Berlin. 2012.
Muller, R.H., Keck C.M. Nanotoxicological Classification system (NCS) - a rational approach to assess the safety & risk of nanoparticles. Annual Meeting of the Society of Dermopharmacy, 1-3 March Berlin. 2012
Baisaeng, N., Shegokar, R., Muller, R.H., Keck, C.M. (2011). Development of ultra-small nanostructured lipid carriers (NLC), AAPS Annual Meeting, Washington D.C. /USA, 23-27 October, T3185.
Peters, D., Muller, R.H., Keck, C.M. (2011). Development and physical stability of nanostructured lipid carriers (NLC) in buffer solution, AAPS Annual Meeting, Washington D.C./USA, 23-27 October, T3215.
Peters, D., Baisaeng, N., Muller, R.H., Keck, C.M. (2011). Novel innovative method for determination of antioxidant capacity vs. conventional DPPH test, AAPS Annual Meeting, Washington D.C./USA, 23-27 October,M1257.
Peters, D., Muller, R.H., Keck, C.M., (2011). Preparation of a gastric resistant NLC dispersion, AAPS Annual Meeting, Washington D.C./USA, 23-27 October, W5115.
Grabo, M., Dunmann, C., Muller, R.H., Keck, C.M. (2011). CapsMorph technology for generation of amorphous oral formulations, AAPS Annual Meeting, Washington D.C./USA, 23-27 October, W4131.
Muller, R.H., Keck, C.M. (2011). Translation of nanoparticle to clinic & marketed product: Prerequisites, strategy, successful examples, Nanodrug Delivery: From the bench to the patient, Rome/Italy, 10-13 October, IL 13.
Okonogi, S., Riangjanapatee, P., Keck, C.M., Muller, R.H. (2011). Effect of surfactant type on physical stability of lycopene-loaded NLC, Annual Joint Meeting, DPhG, 20-23 September, Innsbruck/Austria, PO-233.
Muller, R.H., Shegokar, R., Keck, C.M., Gohla, S. (2011). Nanocrystals in dermal formulations – from the academic idea to the market, Annual Joint Meeting, DPhG, 20-23 September, Innsbruck/Austria, PO-114,
Baisaeng, N., Shegokar, R., Muller, R.H., Keck, C.M. (2011). Development of coenzyme Q10 loaded ultra-small nanostructured lipid carriers (NLC), Annual Joint Meeting, DPhG, 20-23 September, Innsbruck/Austria, PO-100.
Acar Kubart, S., Gennrich, V., Keck. C.M. (2011). Crystalline state of lipid nanoparticles: influence of water content on results. in Annual Meeting of the German Pharmaceutical Society (DPhG), 20-23 September, Innsbruck/Austria, No . PO 11 0.
Muller, R.H., Keck, C.M. (2011). 20 years of drug nanocrystals – state of the art and perspectives, PL-006, Annual Meeting of German Pharmaceutical Society (DPhG), 20-23 September, Innsbruck/Austria
Keck, C.M., Peters, D., (2011). Improved method for determining the antioxidant capacity of lipophilic actives, PO-062, Annual Meeting of German Pharmaceutical Society (DPhG), 20-23 September 2011, Innsbruck/Austria.C. Keck – Anlage113
Meinke, M.C., Haag, S.F., Chen, M., Fahr, A., Bittl, R., Teutloff, C., Fleige, E., Haag, R., Peters, D., Keck, C.M., Lademann, J. (2011). Evaluation of Stability and Penetration Effects of Nano Transporters in the Skin Using Electron Paramagnetic Resonance Spectroscopy, II. 24, International Conference on “Biological Responses to Nanoscale Particles“,11-15 September 2011, Essen/Germany.
Acar-Kubart, S., Keck, C.M. (2011). Contact angle determination: Effect of Sample preparation. in 3rd Pharmaceutical Siences Fair & Exhibition (PharmSciFair), 13-18 June, Prague/Czech Republic.
Kovacevic, A., Savic, S., Vuleta, G., Muller, R.H., Keck, C.M. (2011). Development of polyhydroxy surfactant based lipid nanoparticles in 3rd Pharmaceutical Siences Fair & Exhibition (PharmSciFair). 13-18 June, Prague/Czech Republic .
Keck, C.M., Muller. R.H. (2011). sNLC – a new treatment strategy against AD. in 3rd Pharmaceutical Siences Fair & Exhibition (PharmSciFair), 13-18 June, Prague/Czech Republic.
Shegokar, R., Keck, C.M., Muller, R.H., Gohla, S. (2011). Cosmetic nanocrystals: products and dermal effects, P 123, 6th German-Polish Symposium, 21/22 May, Dusseldorf.
Peters, D., Haag, S.F., Meinke, M.C., Keck, C.M. (2011). TEMPO loaded nanostructured lipid carriers (NLC) to determine the antioxidant capacity of human skin. in 6th German-Polish Symposium 21/22 May, Dusseldorf.
Peters, D., Muller, R.H., Keck. C.M. (2011). Development of fatty alcohol glycoside stabilized nanoemulsions. in 6th German-Polish Symposium, 21/22 May, Dusseldorf.
Keck, C.M. Lipid nanoparticles for dermal application (2011). in 6th German-Polish Symposium, 21/22 May, Dusseldorf.
Acar-Kubart, S., Keck, C.M. (2011). Influence of centrifugation on the crystallinity of nanostructured lipid carriers (NLC). in 6th German-Polish Symposium, 21/22 May, Dusseldorf.
Haag, S.F., M. Chen, A. Fahr, R. Bittl, C. Teutloff, E. Fleige, R. Haag, D. Peters, C.M. Keck, J. Lademann, M. Schafer-Korting, M.C. Meinke. (2011). Electron Paramagnetic Resonance measurements of the skin to evaluate stability and penetration effects of nano carriers. in 15th Annual Meeting of Society for Dermal Pharmacy, 4 - 6 April Vaals/Netherlends
Kovacevic, A., S. Savic, G. Vuleta, R.H. Muller, C.M. Keck. (2011). Preparation and stability investigations on alkyl polyglucoside based solid lipid nanoparticles (SLN) for dermal application. in Controlled Release Society German L ocal C hapter Annual Meeting, 15/16 March, Jena.
Harden, D., R.H. Muller, C.M. Keck. (2011). Lipofundin - 20 year stability investigation of "metastable"nanoemulsions. in Controlled Release Society German Local Chapter Annual Meeting, 15/16 March, Jena.
Chen, R., R.H. Muller, C.M. Keck. (2011). Antioxidative Nanocrystals: correlation between particle size and physico-chemical properties. in Controlled Release Society German Local Chapter Annual Meeting, 15/16 March, Jena.
Baisaeng, N., R. Shegokar, R.H. Muller, C.M. Keck. (2011). Development of lipid carriers with a particle size below 100nm. in Controlled Release Society German Local Chapter Annual Meeting, 15/16 March, Jena.
Al Shaal, L., R. Shegokar, C.M. Keck, R.H. Muller. (2011). Apigenin Nanocrystals for dermal application. in Controlled Release Society German Local Chapter Annual Meeting, 15/16 March, Jena.
Acar-Kubart, S., R.H. Muller, C.M. Keck. (2011). Crystallization behaviour of Nano Lipid Carriers (NLC): effect of lipid phase concentration. in Controlled Release Society German Local Chapter Annual Meeting, 15/16 March, Jena.
Keck, C.M., Muller, R.H. (2010). Nanocrystals - Properties, Production Methods, Stability Issues. Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), 14-18 November, New Orleans/USA
Al Shaal, D., Shegokar, S., Keck, C.M., Muller, R.H. (2010). Novel UV Skin Protective Antioxidant Nanocrystals. Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), 14-18 November, New Orleans/USA
Harden, D., Keck, C.M., Muller, R.H. (2010). Production of concentrated i.v. nanoemulsions: Modified Continental versus English method. Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), 14-18 November, New Orleans/USA
Peters, D., Keck, C.M. (2010). Lipid Nano Carrier for oral administration: lyophilisation & re-dispersibility, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France C. Keck – Anlage 112
Acar, S., Muller, R.H., Keck, C.M. (2010). Nano Lipid Carrier: Prolonged Activity of Menthol in Mouthwash, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Kovacevic, A., Savic, S., Vuleta, G., Muller, R.H., Keck, C.M. (2010). Formulation of SLN & NLC using PEG-free surfactants, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Baisaeng, N., Shegokar, S., Muller, R.H., Keck, C.M. (2010). Development of ultra-small Nano Lipid Carriers (NLC), Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Antaworsakul, P., Patel, M., Okonogi, S., Singh, K.K., Roessner, D., Scherrers, R., Seidel, H., Rimpler, C., Keck, C.M. (2010). Silver Nano Lipid Carriers (sNLC) for the treatment of atopic dermatitis, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Harden, D., Muller, R.H., Keck, C.M. (2010). Nanoemulsions with high oil content as drug carriers for i.v. injection, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Keck, C.M. (2010). Nanocrystals: the most successful nano carriers in pharma, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France
Kovacevic, A., Savic, S., Vuleta, G., Milic, J., Keck, C.M., Muller, R.H. (2010). Formulation and stability investigation on tacrolimus-loaded lipid nanoparticles, V Congress of Pharmacists of Serbia, 13-17 October, Belgrade/ Serbia
Kovacevic, A., Savic, S., Vuleta, G., Milic, J., Keck, C.M., Muller, R.H. (2010). Polyglycerol fatty acid ester based lipid nanoparticles: physical stability and occlusive properties, V Congress of Pharmacists of Serbia, 13-17 October, Belgrade/ Serbia
Muller, R.H., Kovacevic, A., Savic, S., Keck, C.M. (2010). Formulation, physical stability and crystalline status of polyhydroxyl surfactant based SLN and NLC. Annual Meeting of the German Pharmaceutical Society (DPhG), 4-7 October, Braunschweig/Germany
Peters, D., Keck, C.M. (2010). Alkylpolyglycoside stabilized NLC: Influence of Surfactant concentration on particle size & stability. Annual Meeting of the German Pharmaceutical Society (DPhG), 4-7 October, Braunschweig/Germany
Harden, D., Muller, R.H., Keck, C.M. (2010). Highly concentrated 40% nanoemulsions for drug delivery. Annual Meeting of the German Pharmaceutical Society (DPhG), 4-7 October, Braunschweig/Germany
Keck, C.M. (2010). The silver-nanolipid-complex: in vivo efficacy. Annual Meeting of the German Pharmaceutical Society (DPhG), 4-7 October, Braunschweig/Germany
Acar, S., Muller, R.H., Keck, C.M. (2010). Role of ?-modification on physical stability of lipid nanoparticles. Annual Meeting of the German Pharmaceutical Society (DPhG), 4-7 October, Braunschweig/Germany
Kovacevic, A., Savic, S., Milic, J., Muller, R.H., Keck, C.M. (2010). Polyglycerol fatty acid ester based lipid nanoparticles: a physical stability & crystalline status, 8th Central European Symposium on Pharmaceutical Technology, 1 Jun 18 September, Graz/Austria, PNM 11.
Peters, D., Keck, C.M. (2010). Lipidnanopartikel: Vergleich der Matrixstruktur von SLN & NLC, Deutsche Pharmazeutische Gesellschaft (DPHG) - Tag der Pharmazie der Landesgruppe Berlin-Brandenburg, 2 July, P22, Berlin/Germany
Harden, D., Muller, R.H., Keck, C.M. (2010). Hochkonzentrierte Nanoemulsionen zur intravenosen Injektion –eine neue i.v. Formulierung, Deutsche Pharmazeutische Gesellschaft (DPHG) - Tag der Pharmazie der Landesgruppe Berlin-Brandenburg, P12, 2 July, Berlin/Germany
Acar, S., Muller, R.H., Keck, C.M. (2010). Verlangerte Freisetzung von Menthol in Sprays und Losungen mit Lipid-Nanotechnologie, Deutsche Pharmazeutische Gesellschaft (DPHG) - Tag der Pharmazie der Landesgruppe Berlin-Brandenburg,2 July, P1, Berlin/Germany
Patel, M., Singh, K. K., Keck, C.M. (2010). Silver-nanolipid-complex (sNLC): Anti-inflammatory activity in murine mouse model of atopic dermatitis. 11th European Workshop on Particulate Systems (EWPS). 4-5 June, Paris/France
Nikolic, S., Keck, C.M., Muller, R.H. (2010). Lipid nanoparticles for synergistic skin photoprotection. 11th European Workshop on Particulate Systems (EWPS). 4-5 June, Paris/France
Peters, D., Keck, C.M. (2010). Lipid nanoparticles: Differences in polymorphic structures of SLN&NLC. 11th European Workshop on Particulate Systems (EWPS). 4-5 June, Paris/France C. Keck – Anlage 111
Roessner, D., Scherrers, R., Jocks, T., Seidel, H., Keck, C.M. (2010). Silver-nanolipid-complex: mechanism of action using AF4-MALS technology Controlled Release Society German Local Chapter Annual Meeting 2010, March 24, Saarbrucken/Germany
Schwabe, K., Keck C.M. (2010). Silver-nanolipid-complex: In vivo study, Controlled Release Society - German Local Chapter: Annual Meeting 2010, March 24, Saarbrucken/Germany
Patente/Patentanmeldungen:
Keck, C.M., Nanocrystals and amorphous nanoparticles and method for production of the same by a low energy process, in EP11185527.6. 2011.
Vorträge
Konferenzbeiträge und Sonstige:
Keck, C.M.(2014) smartPearlsR new dermal “injection-like” delivery system without use of needle, Menopause, Andropause, Anit-Aging, Wien, 11-13 December (13December)
Keck, C.M.(2014) Flip Flop NLC for improved delivery of natural antioxidants, NutriOx 2014:Nutrition and Ageing, 1 – 3 October, Metz/France (1 October)
Keck, C.M.(2014) Ultrasmall NLC - improved dermal delivery of coenzyme Q10, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, 31 March-3 April (1 April)
Keck, C.M.(2013) Applied Pharmacy: Challenges and Perspectives, Workshop on Applied Pharmacy, University of Applied Sciences Kaiserslautern - Campus Pirmasens, 29 May, Pirmasens/Germany (29 May)
Acar Kubart, S., C.M. Keck, R.H. Muller. (2012). CapsMorphTM – long term preservation of the amorphous state for poorly soluble actives. Engineering of Functional Interfaces (EnFI), 16-17 July, Zweibrucken/Germany (16 July)
Baisaeng, N., Muller, R.M., Keck, C.M. (2012).Development and production of ultra-small lipid nanocarriers (NLC), Engineering of Functional Interfaces (EnFI), 16-17 July, Zweibrucken/Germany (16 July)
Junmahasath ien, T., Muller, R.H., Keck, C.M. (2012). Production of Nanoemulsion (NE) and Lipidnanoparticles in ultra-small scale. Engineering of Functional Interfaces (EnFI), 16-17 July, Zweibrucken/Germany (16 July)
Keck, C.M. (2011). Anti-Aging Pille: Wunschtraum oder Zukunft?, „offentlicher Habilitationsvortrag“, Freie Universitat Berlin, Berlin/Germany (30 November)
Keck, C.M. (2011). Lipid nanoparticles for dermal application, 6th German-Polish Symposium 2011. 21/22 May, Dusseldorf/Germany (21 May)
Keck, C.M. (2010). Nanocrystals: the most successful nano carriers in pharma, Overview of activities in NANOTECHNOLOGIES, Meeting of Nanodata, 24-25 November, Metz/France (24 November)
Keck, C.M. (2010). The silver-nanolipid-complex: in vivo efficacy, Annual Meeting of the German Pharmaceutical Society (DPhG), Braunschweig/Germany (6 October)
Patel, M., Singh, K. K., Keck, C.M. (2010). Silver-nanolipid complex (sNLC): Anti-inflammatory activity in murine mouse model of atopic dermatitis, 11th European Workshop on Particulate Systems (EWPS), 4-5 June, Paris/France (4 June)
“invited lectures”:
Bücher:
Keck, C.M. and R.H. Muller (2012). Moderne Pharmazeutische Technologie (Modern Pharmaceutics),
Lehrbuch fur Studierende der Pharmazie & Nachschlagewerk fur Apotheker in Offizin und Forschung, 2.Aufl.,www.pharmazie-lehrbuch.de
Buchkapitel:
Keck C.M., Muller, R.M., Schafer, K.H. (2014) Nanotaxis for antioxidants to make them biologically active, in Recent advances in redox active plant and microbial products: From basic chemistry to widespread applications in Medicine and Agriculture, Claus Jacob (ed.), Springer, in press
Keck, C. M. Kobierski, S., Mauludin, R., Muller, R. H. (2013) Novel top down technologies: Effective production of ultra-fine drug nanocrystals, in Drug Delivery Strategies for Poorly Water-Soluble Drugs. Douroumis, D., Fahr, A. Wiley, 247-264.
Muller, R.H., R. Shegokar, S. Gohla, C.M. Keck, (2011) Nanocrystals: Production, Cellular Drug Delivery, Current and Future Products, in Intracellular Delivery: Fundamentals and Applications, Fundamental Biomedical Technologies, A. Prokop, Editor., Springer, 411-32.
Keck, C.M., Al Shaal, L., Muller, R.H. (2010) smartCrystals – review of the second generation of drug
nanocrystals, in: Handbook of Materials for Nanomedicine (V. Torchillin, M. M. Amiji, eds.), Pan Stanford Series on Biomedical Nanotechnology, Pan Stanford Publishing, London, 555-580,
Souto, E. B., Keck, C., Muller, R.H., (2010). Technology of lipid nanoparticles (SLN, NLC) as nanocarriers for skin applications: properties, production & cosmetic formulations, in: Cosmetics: Types, Allergies and Applications, Laura M. Hayes (Ed.), Nova Scientific Publishers, Hauppauge, New York, USA, Chapter 3